Abstract
Aim: Improvement in the care and treatment of neonates has contributed to increased survival. In the last few years, nosocomial infection frequency has risen up owing to the increased survival rates in the neonates. Material and
Method: In this study, we retrospectively assessed the prevalence of Pseudomonas infection and antibiotic sensitivity of these microorganism in our neonatal intensive care unit between September 2003-August 2004.
Results: A total of 978 neonates were hospitalized during this period. 146 cultures were collected from 17 patients and Pseudomonas was isolated in 38 of these cultures. Of these 17 patients, 11(64.7%) were premature and 6(35.3%) were mature.The average birth weight was 1807.47±826.9 g(1345-3200 gr), average gestational age was 33.2±4.9 weeks and average postnatal age was 45.05±83.7 hours. Mean hospitalization time was 43±31.5 days. Antibiotics were administered to all cases before Pseudomonas isolation. The best antimicrobial sensitivity was observed with Imıpenem (94%) and Ciprofloxacin (86%) which were the most effective antibiotics for Pseudomonas infections. Of this 38 cultures, 82% were sensitive to amicasin, 80% to piperasilin, 50% to netilmycin.
Conclusion: Appropiate antibiotic selection and improvements in hygiene are required to reduce the incidence of nosocomial infections in neonatal intensive care unit
Keywords: Neonates, nosocomial infection, pseudomonas infection
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