Abstract

Objective: Our aim is to determine the severity, clinical features, presence of complications and outcome differences in  previously  diagnosed  and  newly  diagnosed  Type  1  Diabetes  Mellitus  (T1DM)  patients  followed  up  with  diabetic  ketoacidosis (DKA) in the pediatric intensive care unit.

Material and Methods: This study was conducted retrospectively in a 32-bed tertiary pediatric intensive care unit. The patients were divided into newly diagnosed and previously diagnosed T1DM. All collected data were compared between groups.

Results: 107 patients were included into the study. Most of the patients were male (51.4%). Most of the newly diagnosed patients were in the 6-10 age group (49.2%). When patient complaints were evaluated before admission, the complaint of nausea was statistically higher in previously diagnosed DM patients (p=0.041). The complaints of fatigue, polyuria, polydipsia, and weight loss were statistically higher in newly diagnosed Type-1 DM (p value 0.001, 0.001, 0.001, 0.001, respectively). Hypokalemia was statistically higher in the newly diagnosed DM group during diabetic ketoacidosis treatment (p=0.015). Although there was no difference between intensive care durations, total hospitalization days were statistically longer in newly diagnosed DM patients (p values 0.145, 0.007, respectively). All patients survived.

Conclusion:  The  school  age  group  was  the  most  common  age  group  in  newly  diagnosed  T1DM.  While  polyuria, polydipsia  and  weight  loss  are  common  in  newly  diagnosed  Diabetic  Ketoacidosis  patients;  Vomiting  was  common  in  diabetic ketoacidosis patients with previous diagnosis. Trainings, national advertisements, etc. should be done to increase the knowledge level of patients and families about these symptoms and the disease.

Keywords: children, diabetic ketoacidosis, intensive care

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Copyright and license

Copyright © 2022 The Author(s). This is an open access article distributed under the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited.

How to cite

1.
Özcan S, Akay S, Bozkurt İ, Uyar E, Perk O, Bitkay A, et al. Evaluation of Clinical Differences of Newly Diagnosed and Formerly Diagnosed Pediatric Diabetic Ketoacidosis Patients. Turk J Pediatr Dis [Internet]. 2022 Sep. 20 [cited 2025 Aug. 23];16(5):409-14. Available from: https://turkjpediatrdis.org/article/view/853