Abstract

Objective: Pertussis is a serious public health problem and a major cause of vaccine-preventable deaths under 5 years of age. The aim of this study is to present the clinical data of the patients who were hospitalized with the diagnosis of pertussis/pertussis-like disease.

Material and Methods: Hospitalized 1-4 months old infants diagnosed with pertussis/ pertussis-like disease from January 2018 to September 2018 at l were assessed retrospectively.

Results: A total of 97 patients (51 males, 46 females) were diagnosed with pertussis/pertussis-like disease. Median age of the patients was 2 months (min-max 0.97-3.90). There was spasmodic cough in all cases. Thirty-two (33%) cases had abnormal lung auscultation sounds (rales and/or rhonchi), 5 cases had apnea and 36 cases had tachypnea. Nasopharyngeal smears for pertussis were taken from 31 patients (32%). Twelve from 31 nasopharyngeal smears (39%) were positive for B. pertussis using polymerase chain reaction (PCR). There was no significant difference between pertussis PCR positive group, pertussis PCR negative group and unexamined group in terms of hospital stay and age of patients. Total leucocyte and lymphocyte count in pertussis PCR positive group were significantly higher than in other two groups. Two patients were referred to the intensive care unit due to respiratory distress after their first day of hospitalization. Both received mechanical ventilator support and were discharged with cure.

Conclusion: Pertussis infection causes significant morbidity and mortality in early infancy. Appropriate strategies should be developed to protect these babies.

Keywords: Bordetella pertussis, Koza stratejisi, Maternal aşılama

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Copyright and license

Copyright © 2021 The Author(s). This is an open access article distributed under the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited.

How to cite

1.
Öztek Çelebi FZ, Oğuz MM, Şenel S. Clinical Features of 1-4 Months Old Infants Hospitalized with Pertussis/Pertussis-Like Disease. Turk J Pediatr Dis [Internet]. 2021 Jan. 22 [cited 2025 Aug. 23];15(1):48-51. Available from: https://turkjpediatrdis.org/article/view/821