Abstract

Objective: Wolff-Parkinson-White patern is the most common form of ventricular preexcitation. The aim of this study was to investigate the clinical features of pediatric patients with Wolff-Parkinson-White patern or syndrome and to investigate the results of the follow up.

Material and Methods: The echocardiography database and Holter archive were sorted and a total of 73 children were found to be diagnosed as having Wolff-Parkinson-White Syndrome between January 2000 and December 2017. The medical recordings of these patients were evaluated retrospectively. The demograghic and clinical features and follow–up results were recorded.

Results: A total of 73 patients were diagnosed with Wolff-Parkinson White Syndrome in the determined period. Nine patients were newborns. 15 patients (20%) were admitted to our clinic at least once before diagnosis of Wolff-Parkinson-White syndrome but were missed. 17 patients had conjenital heart disesis,a. 23 patients were completely asymptomatic, 9 patients were diagnosed due to nonspecific symptoms, and the remaining 41 patients were symptomatic patients. 18 of the symptomatic patients referred to our clinic with the recorded supraventricular tachycardia. In 23 patients, transesophageal electrophysiological study was performed for risk assessment. 28 patients underwent catheter ablation during the mean follow-up period of 45.1 ± 43 months.

Conclusion: Although children with Wolff-Parkinson-White Syndrome can be admitted during supraventricular tachycardia, they are mostly diagnosed in symptomatic patients and few are caught incidentally in asymptomatic patients transesophageal electrophysiological study is an effective method in risk assessment. When needed, ablation provides definitive treatment.

Keywords: Children, Supraventricular tachycardia, Wolff-Parkinson-White Syndrome

References

  1. Ekici F, Çetin İİ, Karadeniz LB. Wolff-Parkinson-White Elektrokardiyografik Paterni Saptanan Çocuklarda Klinik Değerlendirme ve Semptomatik Olguların Sunumu. Turkish J Pediatr Dis 2011;5:220-30.
  2. Cohen MI, Triedman JK, Cannon BC, Davis AM, Drago F, Janousek J, et al. PACES/HRS expert consensus statement on the management of the asymptomatic young patient with a Wolff-Parkinson-White (WPW, ventricular preexcitation) electrocardiographic pattern. Heart Rhythm 2012;9:1006-24.
  3. Toni L, Blaufox AD. Transesophageal Evaluation of Asymptomatic Wolff‐Parkinson‐White Syndrome. PACE 2012; 35:519-23.
  4. Yıldırım I, Özer S, Karagöz T, Şahin M, Özkutlu S, Alehan D et al. Wolff-Parkinson-White sendromlu çocuk hastaların klinik ve elektrofizyolojik çalışma ile değerlendirilmesi. Anatol J Cardiol 2015;15:485-90.
  5. Güven H, Levent E, Özyürek AR, Büyükinan M, Aydoğdu, Parlar A. Çocuklarda 2 yıllık holter monitörizasyon deneyimi. Ege J Med 2002;41:15-20.
  6. Işıl Yıldırım, Sema Özer, Tevfik Karagöz, Murat Şahin, Süheyla Özkutlu, Dursun Alehan, Alpay Çeliker. Clinical and electrophysiological evaluation of pediatric Wolff-Parkinson-White patients. Anatol J Cardiol 2015;15:485-90.
  7. Özkaya O, Tunaoğlu S, Koç E, ve ark Yenidoğan Döneminde Bir Wolff-Parkinson-White Sendromu Olgusu. Turkiye Klinikleri J Pediatr 1997;6:77-80.
  8. Smith RF. The Wolff-Parkinson-White syndrome as an aviation risk. Circ J 1964;29:672-9.
  9. Paul T, Guccione P, Garson A. Relation of syncope in young patients with Wolff-Parkinson-White syndrome to rapid ventricular response during atrial fibrillation. Am J Cardiol 1990;65:318-21.
  10. Brugada J, Blom N, Sarquella-Brugada G, Blomstrom-Lundqvist C, Deanfield J, Janousek J, et al. Pharmacological and nonpharmacological therapy for arrhythmias in the pediatric population: EHRA and AEPC-Arrhythmia Working Group joint consensus statement. Europace 2013;15:1337-82.
  11. Özer S, Çeliker A, Karagöz T, Melek E. Transesophageal electrophysiologic study in children and young patients. Turkish J Pediatr 2007;49:45-51.
  12. Bayar N, Canbay A, Ucar O, Aydoğdu S, Diker E. Association of Gerbode-type defect and Wolff-Parkinson-White syndrome with Ebstein’s anomaly/Ebstein anomalisine eşlik eden Gerbode tip defekt ve Wolff-Parkinson-White Sendromu. Anadolu Kardiyol Derg 2010;10:88-91.
  13. Ayabakan C, Güran Ö, Akalın F. Supraventriküler Taşikardi ile Başvuran Konjenital Olarak Düzeltilmiş Büyük Arter Transpozisyonu Olgusu. Turkiye Klinikleri J Pediatr 2008;17:138-42.
  14. Nihei K, Shinomiya N, Kabayama H, , Ikeda C, Hosono T, Aoki T, et al. Wolff-Parkinson-White (WPW) syndrome in isolated noncompaction of the ventricular myocardium (INVM). Circ J 2004;68:82-4.
  15. Fichet J, Legras A, Bernard A, Babuty D. Aborted Sudden Cardiac Death Revealing Isolated Noncompaction of the Left Ventricle in a Patient with Wolff‐Parkinson‐White Syndrome. PACE 2007;30:444-7.
  16. Salerno JC, Chun TU, Rutledge JC. Sinus Bradycardia, Wolff Parkinson White, and Left Ventricular Noncompaction. Pediatr Cardiol 2008;29:679-82.
  17. Vlad P, Rowe RD, Keith JD. The electrocardiogram in primary endocardial fibroelastosis. Br Heart J 1955;17;189.
  18. Çetin MS, Çetin EHÖ. Nonkompakt Kardiyomiyopatide Klinik Triadın Önemli Halkası: Aritmiler. MN Kardiyoloji 2016;23:158-63.
  19. Packer DL, Bardy GH, Worley SJ, Smith MS, Cobb FR, Coleman RE, et al. Tachycardia-induced cardiomyopathy: a reversible form of left ventricular dysfunction. Am J Cardiol 1986;57:563-70.
  20. Aykan HH, Karagöz T, Akın A, İrdem A, Özer S, Çeliker A. Results of radiofrequency ablation in children with tachycardia-induced cardiomyopathy. Anatol J Cardiol 2014;14:625-30.
  21. Sarubbi B, D’Alto M, Vergara P, Calvanese R, Mercurio B, Russo MG, et al. Electrophysiological evaluation of asymptomatic ventricular pre-excitation in children and adolescents. Int J Cardiol 2005;98:207-14.
  22. Atar İ, Özin B. Supraventriküler Taşikardi Tanısı ile Acil Servise Başvuran Hastaya Yaklaşım. TAPE 2006;4:163-7.
  23. Kılıç A, Köse S, Amasyalı B, Yozgat Y, Kul M, Kurşaklıoğlu H ve ark. Kırkbeş Günlük Sütçocuğunda İlaçlara Dirençli Sürekli Supraventriküler Taşikardinin Radyofrekans Kateter Ablasyonla Tedavisi. TAPE 2006;4:242-7.
  24. Philip Saul J, Kanter RJ, Abrams D, Asirvatham S, Bar-Cohen Y, Blaufox AD, et al. PACES/HRS expert consensus statement on the use of catheter ablation in children and patients with congenital heart disease. Heart Rhythm 2016;13:e252-89.

Copyright and license

Copyright © 2021 The Author(s). This is an open access article distributed under the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited.

How to cite

1.
Güler M, Cengiz S, Ceviz N. Clinical Features of Children With Wolff-Parkinson-White Syndrome. Turk J Pediatr Dis. 2021;15(2):93-98. https://doi.org/10.12956/tchd.638639