Abstract

Objective: The most common viral agents causing acute diarrhea in children are rotavirus and enteric adenovirus, respectively. In diarrhea cases caused by these both factors, the clinical manifestation of children can deteriorate very rapidly. Vomiting, dehydration, and metabolic acidosis seen especially in children cause indications for receiving inpatient treatment. In this study, we aimed to evaluate the epidemiologic aspects of enteric adenovirus and rotavirus diarrhea cases in the inpatients treated in our hospital, to analyze the demographic data, and to show what treatments were applied.

Material and Methods: Data of a total of 1281 pediatric patients between 0 and 14 years old admitted to Yeni Yüzyıl University Medical Faculty Gaziosmanpaşa Hospital between 1 January 2016- 31 December 2017 due to diarrhea were evaluated retrospectively. The study group consisted of acute-gastroenteritis-prediagnosed 443 patients with no parasites on stool microscopy and without any Salmonella-Shigella spp. growth in the stool culture. These patients had also test results of rotavirus and enteric adenovirus antigens, and stayed at hospital for at least 24 hours. Pearson’s chi-square test and t test were used for statistical analysis, and p<0.05 was considered significant.

Results: A total of 443 (34.6%) of the 1281 patients with diarrhea were hospitalized. Thirty-eight (2.9%) patients had a positive enteric adenovirus test, and 95 (7.4%) had rotavirus. The most common complaints were nausea, vomiting, fatigue, and fever. Abdominal pain was the least common complaint. Probiotic use alone was 61% in patients with rotavirus diarrhea, and 63.2% in patients with enteric adenovirus infection. Antimicrobial antibiotics were used in 58% of patients with negative rotavirus and enteric adenovirus antigens. Antiprotozoal-effective antibiotics were the least preferred drugs in the patients with either positive or negative test results for rotavirus and enteric adenovirus antigens.

Conclusion: Viral factors should be considered in childhood diarrhea. In the treatment of diarrhea, the replacement of the lost fluid should be planned primarily. Laboratory tests for antibacterial or antiprotozoal antibiotics should be taken into consideration. Early diagnosis of rotavirus and enteric adenovirus antigens can be made using rapid diagnostic tests in the hospitalized pediatric patients with diarrhea. Thus, we consider that unnecessary antibiotic use can be prevented by symptomatic treatments in these patients.

Keywords: Acute viral diarrhea, Adenovirus, Admission to the hospital, Rotavirus

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Copyright © 2020 The Author(s). This is an open access article distributed under the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited.

How to cite

1.
Bayırlı Turan D. An Evaluation in Terms of Rotavirus and Enteric Adenovirus Infection in Children With Acute Diarrhea Requiring in Patient Treatment. Turk J Pediatr Dis [Internet]. 2020 May 29 [cited 2025 Aug. 23];14(3):220-4. Available from: https://turkjpediatrdis.org/article/view/688