Abstract
Cytomegalovirus (CMV) can lead serious clinical presentations with various organ system involvements in individuals with primary or acquired immune deficiency. CMV colitis may present with clinic symptoms such as abdominal pain, diarrhea, hematochezia, melena and fever. Stricture due to CMV colitis is a very rare complication. We discuss ileum and colon stricture due to CMV colitis in an immunodeficient patient in this paper.The two-year-old male patient was being followed-up with combined immunodeficiency and the bare lymphocyte syndrome. He was hospitalized at the pediatric intensive care unit for diarrhea and pneumonia for the last month. CMV PCR was positive in the tests and ganciclovir was therefore added to the treatment. Colonoscopy was performed for fecal occult blood by the pediatric gastroenterology unit. The biopsy result was reported as CMV colitis.The patient developed ileus during follow-up, and the colon graph with contrast revealed a narrow colon segment with the contrast agent unable to pass to the terminal ileum. Laparotomy was performed and strictures observed in the terminal ileum and the ascending colon. An ileocolic anastomosis was performed by resecting the bowel loops affected by stricture. The histomorphologic findings were reported as CMV colitis. The patient was discharged and referred for follow-up to the pediatric service.Cytomegalovirus is an opportunistic virus that can lead to the infection of the gastrointestinal system in individuals with immunodeficiency. CMV colitis and stricture should be considered in the differential diagnosis in immunodeficient children with ileus symptoms.
Keywords: Severe combined immunodeficiency, Bare lymphocyte syndrome, Ileus, Colitis
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Copyright and license
Copyright © 2019 The Author(s). This is an open access article distributed under the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited.
