Abstract
Drug rash with eosinophilia and systemic symptoms (DRESS) is characterized by a severe multiorgan hypersensitivity reaction that usually appears after a 3–6-week exposure to certain drugs, including anticonvulsants. Many reports have revealed that human herpesvirus 6 (HHV-6) reactivation contributes to the development of DRESS. In addition, recent articles have shown that reactivation of other herpesviruses such as human herpesvirus 7 (HHV-7), Epstein-Barr virus (EBV) and cytomegalovirus (CMV) might be also implicated in development of DRESS. Here we report development of the DRESS syndrome and concurrent presence of CMV viral load in a 2-year-old girl who was on phenytoin prophylaxis for febrile seizure
Keywords: Cytomegalovirus infection, Drug rash with eosinophilia and systemic symptoms, DRESS syndrome, Intravenous immunoglobulin
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