Öz

Eozinofili ve sistemik semptomların eşlik ettiği ilaç döküntüsü (DRESS) genellikle antikonvülzanların dahil olduğu birtakım ilaçlara, 3-6 hafta maruz kaldıktan sonra görünen şiddetli çoklu organ aşırı duyarlılık reaksiyonu ile karakterizedir. Birçok çalışmada insan Herpes Virüs 6 (HHV-6) reaktivasyonunun DRESS gelişimine katkıda bulunduğu gösterilmiştir. Bununla birlikte yakın dönemdeki çalışmalarda diğer Herpes virüslerden, Herpes virüs 7 (HHV-7), Ebstein-Barr virüs (EBV) ve Sitomegalovirus (CMV) reaktivasyonunun DRESS gelişimiyle ilişkili olduğu gösterilmiştir. Burada febril konvülsiyon profilaksisi için fenitoin kullanmakta olan 2 yaşında bir kız çocuğunda DRESS gelişimi ve eş zamanlı CMV viral yük varlığı gösterilmiştir.

Anahtar Kelimeler: Sitomegalovirus enfeksiyonu, Eozinofili ve sistemik semptomların eşlik ettiği ilaç döküntüsü, DRESS sendromu, İntravenöz immunoglobulin

Referanslar

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Telif hakkı ve lisans

Nasıl atıf yapılır

1.
Haytoğlu Z. Eozinofili ve Sistemik Semptomların Eşlik Ettiği İlaç Döküntüsü (Dress ) ile Eş Zamanlı Sitomegalovirus Enfeksiyonu: Bir Olgu Sunumu. Turk J Pediatr Dis [Internet]. 2017 Apr. 1 [cited 2025 May 24];11(1):56-8. Available from: https://turkjpediatrdis.org/article/view/478