Abstract

Objective: Our aim was to determine the epidemiological, clinical, radiological, microbiological properties and the treatment results of cases with tuberculosis and the relationship of these properties with disease stages.

Material and Methods: Patients diagnosed with latent and active tuberculosis and children who had contacted an adult tuberculosis case and had been followed up by the infectious diseases department of our hospital between May 2006 and May 2007 were included in the study. All were evaluated retrospectively for their complaints, physical examination findings, laboratory findings, BCG vaccination situation, treatment modalities and complications due to the treatment. results: A total of 418 cases were included in our study. The mean age was 7.9 ± 3.7 years and 217 (52%) were female. Cases were grouped as contact (n: 20, 4.8%), latent infection (n: 322, 76.7%) and active disease (n: 76, 18.1%). It was demonstrated that active disease was usually seen in cases younger than 5 years old and latent infection in cases greater than 5 years old (p:0.04). The main complaint was nonproductive cough (38.7%) in the latent group and secretory cough with night sweating (25%) in the active group (p:0.01). There was pulmonary involvement in 55 (72%) of the active cases. The second most common location of the disease was the lymph nodes (13%). The BCG vaccination rate was 91%. The occurrence of active disease was decreased significantly as the number of BCG scars increased. The PPD test was positive in 85% of the cases. The most common findings on chest x-rays were bronchopneumonic infiltration (LI: 4.7%, AD: 28.9%), peribronchial lymphadenopathy (LI: 4.7%; AD: 19.9%) and atelectasis (LI: 4.7%; AD: 11.8%). Only 3 cases received directly observed treatment (DOT). During the treatment, 18 (4.3%) cases had a complication such as increased levels of AST and ALT and 3 cases had allergic skin reactions due to INH. The treatment of 90% of cases was completed whereas 10% of cases did not come for follow-up.conclusion: To fight tuberculosis, which is an important person and community health problem, all child and adult patients should be treated and followed up at a single center organised for this aim

Keywords: BCG, Childhood, Latent tuberculosis infection, Tuberculosis

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How to cite

1.
Bozabalı S, Olukman Ö, Cangar Ş. Tuberculosis Cases Evaluation of the Clinical Properties of Childhood. Turk J Pediatr Dis [Internet]. 2017 Apr. 1 [cited 2025 May 24];11(1):27-33. Available from: https://turkjpediatrdis.org/article/view/473