Abstract

Congenital toxoplasmosis is a rare intrauterine infection caused by acute infection of the mother during pregnancy. Congenital toxoplasmosis can present in a spectrum from a mild form to a severe form including chorioretinitis, meningitis, hydrocephaly and intracranial calcification. Although possibility of passage to the fetus is low in early pregnancy, the severity and sequela risk are high. Diagnosis depends on the demonstration of the parasites itself, its DNA extracts, or antibodies against the surface antigens of the parasites. Here we present two cases of congenital toxoplasmosis that did not have antenatal follow-up. The family of the first case arrived from Syria due to war and the mother did not receive any antenatal care because of poor living conditions after the forced migration. The second case was the fourth pregnancy of the mother who did not have any antenatal care.Finally, congenital toxoplasmosis is an insidious and fatal disease. Early treatment during pregnancy or the postnatal period has positive effects on the prognosis. Antenatal care is important in the diagnosis. We would like to underline the importance of informing both refugees and natives about antenatal care and the necessity of taking preventive measures for refugees by the authorities

Keywords: Infant, Congenital, Toxoplasmosis, Newborn

References

  1. Carter AO, Frank JW. Congenital toxoplasmosis: Epidemiologic features and control. CMAJ 1986;135: 618–23.
  2. Uludağ S, Madazlı R, Sen C, Ocak V. Gebelik ve toksoplazmozisde klinik yönetim. Perinatoloji Dergisi 1993;1:165-9.
  3. Desmonts G, Couvreur J. Congenital toxoplasmosis. Prospective study of the outcome of pregnancy in 542 women with toxoplasmosis acquired during pregnancy. Ann Pediatr (Paris) 1984;31:805-9.
  4. Mandell GL, Benett JE, Dolin R. Principles and practice of infectious diseases. In: Montoya JG, Kovacs JA, Remington JS (eds). Toxoplasma Gondii. 6th ed. Newyork: Churchill Livingstone, 2005;2:3170-228.
  5. Magi B, Migliorini L. Western blotting for the diagnosis of congenital toxoplasmosis. New Microbiol 2011;34:93-5.
  6. Remington JS, McLeod R, Wilson CB, Desmonts G. Toxoplas- mosis. In: Remington, JS, Klein, JO, Wilson, CB (eds). Infectious Diseases of the Fetus and Newborn Infant, 7th ed. Philadelphia: Elsevier Saunders, 2011:918.

How to cite

1.
Akçalı M, Özlü F, Esen E, Çay Ü, Batun İ, Yıldızdaş HY, et al. Two Newborn Cases with Congenital Toxoplasmosis. Turk J Pediatr Dis [Internet]. 2017 Jun. 1 [cited 2025 May 25];11(2):129-33. Available from: https://turkjpediatrdis.org/article/view/462