Abstract
Objective: To evaluate the relationship of metabolic parameters with serum uric acid and percentage of body fat in obese adolescents.
Material and Methods: A total 124 adolescents between 10-16 years of age were included in the study. Two groups were created as normal weight (Control, n=40) and obese (n=84). The obese children were also divided into 2 groups according to the presence or absence of Metabolic Syndrome (MS); Obese MS (-) (n=45) and Obese MS (+) (n=39). Bioelectrical impedance analysis was used to measure the percentage of body fat (BF %).
Results: The values of body mass index- standard deviation score (BMI-SDS), waist circumference (WC), total body fat-standard deviation score (BF% -SDS), systolic and diastolic blood pressure (BP), fasting insulin, HOMA-IR, triglyceride, HDL and uric acid were significantly different as expected (p<0.001), whereas the fasting blood glucose, total cholesterol and LDL values were similar (p=0.41, p=0.70 and p=0.28, respectively). Percentage of total body fat - standard deviation score and uric acid was significantly correlated with body BMI-SDS, waist circumference (WC), systolic and diastolic BP, fasting insulin, HOMA-IR, triglyceride and HDL (p<0.001). In the multiple linear regressions, it was demonstrated that BF%-SDS was significantly related to the systolic BP (p<0.005), WC (p<0.001) and uric acid (p<0.005).
Conclusion: Total body fat measured via bioelectrical impedance analysis and uric acid had a close relationship with MS components and may be a useful predictive marker for MS diagnosis
Keywords: Bioelectrical impedance analysis, Body fat percentage, Metabolic syndrome, Uric acid
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Copyright © 2016 The Author(s). This is an open access article distributed under the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited.
