Abstract

Objective: In our study we aimed to evaluate the findings of female patients presenting with a complaint of the onset

of puberty according to the etiological factors and to discuss the findings in the literature.

Material and Methods: Ninety-six girls presenting to the pediatric endocrinology clinic patients were enrolled in

the study. Anthropometric measurements and pubertal status of the patients were evaluated. In the evaluation of

patients with suspected early puberty, follicle stimulating hormone (FSH), Luteinising Hormone (LH), estradiol (E2),

dehydroxyepiandrostenedione sulfate (DHEA-SO4), 17-hydroxyprogesterone (17OHP) levels, and luteinizing hormone

releasing hormone (LHRH) stimulation test results were used. The bone age and pelvic ultrasound results were recorded.

Results: The mean age of the patients was 8.38 ± 1.72 years. We found premature thelarche in 14.6% of the patients

(n = 14), premature pubarche in 4.2% (n = 4), premature menarche in 3.1% (n = 3), and precocious puberty in 8.3% (n =

8) while 21.9% (n = 21) were normal variants of pubertal development. 46.9% of admitted patients (n = 45) had normal

pubertal development, 22.9% (n = 22) had an acceleration in pubertal development over eight years. 21.9% (n = 21) of

patients had atypic pubertal development.

Conclusion: The decrease in the age of the onset of puberty has increased applications to the endocrine clinic. Most of

the applications are normal variants of puberty. We wanted to highlight the good diagnostic evaluation of these patients

in this study.

Keywords: Precocious puberty, Girl

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Copyright and license

How to cite

1.
Eklioğlu BS, Atabek ME, Akyürek N, Sarıkaya E. The Etiologic Distribution and Clinical Features of Cases Presenting with the Findings of Puberty to the Pediatric Endocrinology Clinic. Turk J Pediatr Dis [Internet]. 2016 Dec. 1 [cited 2025 May 24];10(4):233-6. Available from: https://turkjpediatrdis.org/article/view/361