Kızıl ile İlişkili Nadir Bir Komplikasyon: Akut Hepatit

Şerife Yılmaz; Şerife Yılmaz; Ali Osman Köksal; Aslı Çelebi Tayfur; Güler Selen; Osman Özdemir; Nesibe Andıran

Case Report

Turk J Pediatr Dis 2015; 9(2): 137-139.

PDF

A Rare Complication Associated with Scarlet Fever: Acute Hepatitis

Authors

Şerife Yılmaz

Ali Osman Köksal

Aslı Çelebi Tayfur

Güler Selen

Osman Özdemir

Nesibe Andıran

Affiliations

Turk J Pediatr Dis 2015; 9(2): 137-139.

Published: June 1, 2015

Abstract

The most common cause of tonsillopharyngitis is group A beta hemolytic streptococcal infection in children. Group A beta hemolytic streptococcus strains that produce erythrogenic exotoxins cause a typical exanthematous disease called scarlet fever. Complications are well described. Hepatitis is a rare complication. We present a 7-year old girl with scarlet fever and elevated liver transaminases in this report. Viruses that lead to hepatitis were not demonstrated. Group A beta hemolytic streptococcus was isolated from the throat culture of the patient. Hepatitis should not be overlooked in patients with group A beta hemolytic streptococcal infections

Keywords: Hepatitis, Scarlet fever, Streptococcus

References

Steer AC, Danchin MH, Carapetis JR. Group A streptococcal infections in children. J Paediatr Child Health 2007;43:203-13.
Wong SSY, Yuen KY. Streptococcus pyogenes and re-emergence of scarlet fever as a public health problem. Emerging Microbes & Infections 2012;1:e2;doi:10.1038/emi.2012.9 Published online 11 July 2012
Gutiérrez Junquera C, Escudero Canto MC, Ruiz Cano R, Cuartero del Pozo I, Gil Pons E. Cholestatic hepatitis as initial manifestation of scarlet fever. An Pediatr (Barc) 2003;59:193–4.
Gómez-Carrasco JA, Lassaletta A, Ruano D. Acute hepatitis may form part of scarlet fever. An Pediatr (Barc) 2004;60:382–3.
Gidaris D, Zafeiriou D, Mavridis P, Gombakis N. Scarlet fever and hepatitis: A case report. Hippokratia 2008;12:186–7.
Girisch M, Heininger U. Scarlet fever associated with hepatitis-A report of two cases. Infection 2000; 28:251–3.
Elishkewitz K, Shapiro R, Amir J, Nussinovitch M. Hepatitis in scarlet fever. Isr Med Assoc J 2004;6:569-70.
Norrby-Teglund A, Chatellier S, Low DE, McGeer A, Green K, Kotb M. Host variations in cytokine responses to superantigens determine the severity of invasive group A streptococcal infection. Eur J Immunol 2000;30:3247-55.
Brody H, Smith LW. The visceral pathology in scarlet fever and the related Streptococcus infections. Amer J Path 1936;12:373- 394.5.
Stevens DL. Streptococcal toxic-shock syndrome: Spectrum of disease, pathogenesis, and new concepts in treatment. Emerg Infect Dis 1995;1:69-78.
Mcmahon HE, Mallry FB. Streptococcus hepatitis. Am J Pathol 1931;7:299-325.
Kocak N, Ozsoylu S, Ertugrul M, Ozdol G. Liver damage in scarlet fever. Descriptions of two affected children. Clin Pediatr (Phila) 1976;15:462-4.
Robbens E, De Man M, Schurgers M, Boelaert J, Lameire N. Systemic complications of streptococcal scarlet fever: Two case reports and a review of the literature. Acta Clin Belg 1986;41: 311-8.
Jansen TL, Janssen M, de Jong AJ, Jeurissen ME. Post strep- tococcal reactive arthritis: A clinical and serological description, revealing its distinction from acute rheumatic fever. J Intern Med 1999;245:261-7.
Demers B, Simor AE, Vellend H, Schlievert PM, Byrne S, Jamieson F, et al. Severe invasive group A streptococcal infections in Ontario, Canada: 1987-1991. Clin Infect Dis 1993;16:792-800.

Copyright and license

How to cite

Yılmaz Ş, Yılmaz Ş, Köksal AO, Tayfur AÇ, Selen G, Özdemir O, et al. A Rare Complication Associated with Scarlet Fever: Acute Hepatitis. Turk J Pediatr Dis [Internet]. 2015 Jun. 1 [cited 2025 May 25];9(2):137-9. Available from: https://turkjpediatrdis.org/article/view/340

Download citation

[ref1] Steer AC, Danchin MH, Carapetis JR. Group A streptococcal infections in children. J Paediatr Child Health 2007;43:203-13.

[ref2] Wong SSY, Yuen KY. Streptococcus pyogenes and re-emergence of scarlet fever as a public health problem. Emerging Microbes & Infections 2012;1:e2;doi:10.1038/emi.2012.9 Published online 11 July 2012

[ref3] Gutiérrez Junquera C, Escudero Canto MC, Ruiz Cano R, Cuartero del Pozo I, Gil Pons E. Cholestatic hepatitis as initial manifestation of scarlet fever. An Pediatr (Barc) 2003;59:193–4.

[ref4] Gómez-Carrasco JA, Lassaletta A, Ruano D. Acute hepatitis may form part of scarlet fever. An Pediatr (Barc) 2004;60:382–3.

[ref5] Gidaris D, Zafeiriou D, Mavridis P, Gombakis N. Scarlet fever and hepatitis: A case report. Hippokratia 2008;12:186–7.

[ref6] Girisch M, Heininger U. Scarlet fever associated with hepatitis-A report of two cases. Infection 2000; 28:251–3.

[ref7] Elishkewitz K, Shapiro R, Amir J, Nussinovitch M. Hepatitis in scarlet fever. Isr Med Assoc J 2004;6:569-70.

[ref8] Norrby-Teglund A, Chatellier S, Low DE, McGeer A, Green K, Kotb M. Host variations in cytokine responses to superantigens determine the severity of invasive group A streptococcal infection. Eur J Immunol 2000;30:3247-55.

[ref9] Brody H, Smith LW. The visceral pathology in scarlet fever and the related Streptococcus infections. Amer J Path 1936;12:373- 394.5.

[ref10] Stevens DL. Streptococcal toxic-shock syndrome: Spectrum of disease, pathogenesis, and new concepts in treatment. Emerg Infect Dis 1995;1:69-78.

[ref11] Mcmahon HE, Mallry FB. Streptococcus hepatitis. Am J Pathol 1931;7:299-325.

[ref12] Kocak N, Ozsoylu S, Ertugrul M, Ozdol G. Liver damage in scarlet fever. Descriptions of two affected children. Clin Pediatr (Phila) 1976;15:462-4.

[ref13] Robbens E, De Man M, Schurgers M, Boelaert J, Lameire N. Systemic complications of streptococcal scarlet fever: Two case reports and a review of the literature. Acta Clin Belg 1986;41: 311-8.

[ref14] Jansen TL, Janssen M, de Jong AJ, Jeurissen ME. Post strep- tococcal reactive arthritis: A clinical and serological description, revealing its distinction from acute rheumatic fever. J Intern Med 1999;245:261-7.