Abstract
Blood group incompatibility is the most common cause of hemolytic anemia in the early newborn period. The widespread use of anti-D gammaglobulin in the last four decades has decreased the rate of Rh incompatibility and increased the rate of minor blood group incompatibility in the etiology of newborn hemolytic anemia. It is important to consider minor group incompatibility in newborn babies with hemolysis in peripheral blood smears but without major blood group incompatibility. The clinical picture with minor blood group incompatibility may vary from subclinical hemolysis to active hemolysis and newborn jaundice that necessitates transfusion. We present a case with symptoms of severe anemia in the early newborn and even in the fetal period, in whom hemolysis was controlled with intravenous immunoglobulin
Keywords: Hemolytic anemia, Intravenous immunoglobulin, Minor blood group incompatibility, Newborn
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