Abstract

Early retinal change and evaluate its progression in children and adolescents diagnosed with insulin dependent diabetes mellitus we examined in 20 Turkish children (8 female, 12 male ). Thein mean age was 13.1 ± 3.9 years with mean diabetes duration of 4.9 ± 3.1 years. Direct ophtalmoscopy and fluorescein fundus angiography (FFA) were performed at the beginning and at and the end of two years follow-up period. The stage of diabetic retinopathy (DR) was evaluated in six stages according to ''Madison modification of Airlie House Classification of Diabetic Retinopathy”. We also considered age, pubertal stage, disease duration, arterial blood pressure, microalbuminuria and HbA1c levels. Retinopathy of varying stage was detected with direct ophtalmoscopy in 2 cases (15 %) and FFA in 6 cases (30 %) respectively. A significant statistical relationship was present between the stage of the DR and patient age. DR was present in 60 % of the patients with a disease duration exceeding 5 years. In the two years follow-up of these patients, regression was noted in 3, new retinal changes consistent with stage 2 and 3 appeared in two patients. A significant positive correlation was present between HbA1c and retinal changes; microalbuminuria and retinal changes. No DR was noted in prepubertal cases.

Conclusion: Because DR may give no symptom early in disease course, routine eye examination must be done regularly in diabetic patients. In early stages; FFA is more sensitive than direct ophtalmoscopy. Regression changes are possible with close follow-up of these cases and the maintenance of good metabolic control of the retinal

Keywords: Insulin dependent diabetes mellitus, retinopathy, fluorescein fundus angiography

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Copyright and license

Copyright © 2008 The Author(s). This is an open access article distributed under the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited.

How to cite

1.
İşgüven P, Çizmecioğlu F, Yıldız M, Arslanoğlu İ, Horoz H, Horoz H, et al. EARLY STAGE DIAGNOSIS AND FOLLOW-UP OF THE DIABETIC RETINOPATHY IN CHILDREN AND ADOLESCENTS WITH INSULIN DEPENDENT DIABETES MELLITUS. Turk J Pediatr Dis [Internet]. 2008 Aug. 1 [cited 2025 Jul. 4];2(1):28-34. Available from: https://turkjpediatrdis.org/article/view/24