Abstract

Methemoglobinemia is a disorder characterized by the presence of a higher than normal level of ferric (Fe+3) rarer man ferrous (Fe+2) hemoglobin. It may be in two forms, congenital or acquired methemoglobinemia. It is known that many agents can cause acquired methemoglobinemia. If the blood methemoglobin level reaches 55%, it can be lethal. Prompt care is needed in this situation. Here, a 4-month-old boy with acquired methemoglobinemia due to prilocaine use is presented. Methylene blue was used in the treatment of this case. The treatment enabled a dramatic improvement and was life saving

Keywords: Children, Local anesthesia, Methemoglobinemia, Prilocaine, Circumcision

References

  1. DeBaun MR, Vichinsky E. Hereditary methemoglobinemia (Chapter 462, Hemoglobinopathies). In: Nelson Textbook of Pediatrics. 18th edition, Behrman & Kliegman& Jenson; 2007:2032-33.
  2. Trapp L, Will J. Acquired methemoglobinemia revisited. Dent Clin North Am 2010;54:665-75.
  3. Benini D, Vino L, Fanos V. Acquired methemoglobinemia: A case report. Pediatr Med Chir 1998;20:411-13.
  4. Türkiye Çocuk Hast Derg/Turkish J Pediatr Dis / 2013; 2: 86-88
  5. Frey B, Kehrer B. Toxic methaemoglobin concentrations in premature infants after application of a prilocaine containing cream and peridural prilocaine. Eur J Pediatr 1999;158:785-88.
  6. Akbayram S, Akgün C, Doğan M, Gündogdu M, Caksen H, Faik Öner A. Acquired methemoglobinemia due to application of prilocaine during circumcision. J Emerg Med 2010. [Epub ahead of print]
  7. Guay J. Methemoglobinemia related to local anesthetics: A summary of 242 episodes. Anesth Analg 2009;108:837-45.
  8. Soeding P, Deppe M, Gehring H. Pulse-Oximetric measurement of Prilocaine- Induced Methemoglobinemia in regional anesthesia. Anesth Analg 2010. [Epub ahead of print].

Copyright and license

Copyright © 2013 The Author(s). This is an open access article distributed under the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited.

How to cite

1.
Toksöz A, Aydoğmuş Ü, Akın M, Keskin G, Tavil B. A Case of Methemoglobinemia Developing Due to Local Prilocaine Usage Prior to Circumcision. Turk J Pediatr Dis [Internet]. 2013 Aug. 1 [cited 2025 Aug. 22];7(2):86-8. Available from: https://turkjpediatrdis.org/article/view/237