Abstract
Patent ductus arteriosus (PDA) causing large left-to-right shunts may lead to congestive heart failure, necrotizing enterocolitis, bronchopulmonary dysplasia, intracranial hemorrhage, and death in extremely-low-birthweight premature infants. Optimal timefor surgical ligation of PDA in extremely-low-birth-weight premature infants remains controversial.Herein, we report 3 patients who had intestinal, renal, and pulmonary complications due to severe PDA. One patient’s ductus was refractory to medical treatment while the remaining2 patients could not receive medical treatment because of contraindications. We suggest that early surgical ligation should be considered in extremely-low-birth-weight premature infants with PDA refractory to medical treatment or in those who have contraindications for medical treatment
Keywords: Patent ductus arteriosus, surgery, ligation, very low birth weight
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Copyright and license
Copyright © 2012 The Author(s). This is an open access article distributed under the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited.