Abstract

An association between hydantoin taken during pregnancy and congenital abnormalities was defined as “fetal hydantoin syndrome”(FHS). Associated minor congenital abnormalities include digit and nail hypoplasia, developmental delay, typical facial appearance, rib anomalies, abnormal palmar creases, hirsutism, and low hairlines. Serious defects such as cardiovascular malformations, cleft lip or palate, and inguinal hernia may also be associated with this syndrome. In this case report, a 13-month-old girl with fetal hydantoin syndrome whose mother had received phenytoin throughout pregnancy has been presented. Her physical examination revealed global developmental delay, craniofacial dysmorphism, and pes equino varus. The patient did not have the cardiovascular malformations associated with FHS.The aim of this case report is to promote awareness among pediatricians regarding the importance of recognizing FHS in infants with congenital abnormalities

Keywords: Anticonvulsants, infant

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How to cite

1.
Çetin FH, Arhan E, Kurt AN, Soysal Ş, Hirfanoğlu T, Serdaroğlu A. FETAL HYDANTOIN SYNDROME. Turk J Pediatr Dis [Internet]. 2012 Aug. 1 [cited 2025 May 24];6(2):106-10. Available from: https://turkjpediatrdis.org/article/view/182