Abstract

Excessive phosphate intake, intestinal calcium malabsorption, hypomagnesemia, maternal hyperparathyroidism, maternal vitamin D deficiency can cause late onset neonatal hypocalcemia. In this paper we present a boy who has late onset hypocalcemia secondary to maternal vitamin D deficiency and parathyroid adenoma. A thirteen day old boy was admitted to hospital with the complaint of trembling and flickering in the eyelids. He was term and 4600 g of weight and his physical examination was normal. In laboratory investigation; Ca = 4.6 mg/dl (8.510.5) P=7.6 mg/dl (2.2-6.5) ALP= 1617 U/L, Mg=0.87mg/dl (1.5-2.1), PTH =56.4 pg/ml , serum glucose and electrolytes was normal. 200 mg/kg/dose %10 Ca gluconate and for hypomagnesemia 0,2 ml/kg %50 MgSO treatment was adjusted. Despite his magnesium level was normal (Mg= 1.82 mg/dl) after the theraphy, hypocalcemia persisted so the other causes of hypocalcemia evaluated. Maternal laboratory investigation reveals us severe 25OH vit D deficiency (< 5 ng/ml) and secondary hyperparathyroidism (PTH=226 pg/ml), her Ca, P, ALP, Mg levels was in normal ranges. In the ultrasonographic examination of maternal parathyroid gland, parathyroid adenoma detected. Oral calcium and calcitriol 0.125 mcg/ day theraphy adminestered and at the seventh day of theraphy patient's serum Ca; P, ALP, Mg levels was normal. Parathyroid adenoma secondary to hyperparathyroidism due to maternal vitamin D deficiency is a rare cause of late onset neonatal hypocalcemia but it should be necessarily considered that in the populations which women could not utilize sunshine adequately because of their lifestyle, ethnicity and religion, maternal vitamin D deficiency and neonatal hypocalcemia can occur easily

Keywords: Hypocalcemia, Parathyroid Adenoma, Vitamin D Deficiency.

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Copyright © 2007 The Author(s). This is an open access article distributed under the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited.

How to cite

1.
Kanmaz G, Aycan Z, Çetinkaya E, Kızılateş SÜ. LATE ONSET NEONATAL HYPOCALCEMIA SECONDARY TO MATERNAL VITAMİN D DEFICIENCY AND PARATHYROID ADENOMA. Turk J Pediatr Dis [Internet]. 2007 Apr. 1 [cited 2025 Aug. 23];1(2):37-41. Available from: https://turkjpediatrdis.org/article/view/18