Abstract

Alopecia areata, which is frequently seen in dermatology policlinics, is known to be an organ specifi c autoimmune disease appearing with a genetic tendency and environmental triggering factors and is often associated with other organ specifi c autoimmune diseases. Autoimmune polyglandular syndromes are defi ned for the association of alopecia with other autoimmune diseases. Autoimmune polyglandular syndromes (APS) are divided into 4 major types as type 1, 2, 3, and 4. Alopecia appears in all types, especially in type 3 of APS. For the diagnosis of APS type 3, besides the presence of autoimmune thyroid disease, another autoimmune disease except Addison’s disease or hypoparathyroidism is required. In 2001, Betterle subdivides APS type 3 into four subgroups (Type 3A, 3B, 3C, and 3D) and coincidence of autoimmune thyroid disease with alopecia is classifi ed as type 3C.Here, 6-year-old male patient with the diagnosis of alopecia areata and his brother diagnosed as alopecia universalis when he was 5-year-old eventually had polyglandular involvement are presented to emphasize associated autoimmune diseases and genetic studies

Keywords: Alopecia areata, autoimmune polyglandular syndromes

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Copyright and license

Copyright © 2010 The Author(s). This is an open access article distributed under the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited.

How to cite

1.
Erdoğan FG, Ergür AT, Güven M, Gürler A. FAMILIAL ALOPECIA AND AUTOIMMUNE POLYGLANDULAR SYNDROME TYPE 3. Turk J Pediatr Dis [Internet]. 2010 Apr. 1 [cited 2025 Jul. 18];4(4):229-35. Available from: https://turkjpediatrdis.org/article/view/122