Abstract

Aim: To evaluate the prevalence, underlying causes, clinical course, and outcomes of the neonatal hyperglycemia. Patient and method: Among the all patients that hospitalized in our neonatal intensive care unit (NICU) for any reason between November 2008 and February 2010, the 112 patients with a plasma glucose level of ≥180 mg/dl were enrolled into the study.

Results: Of the 112 hyperglycemic patients, 52 (46.4%) were preterm and 60 (53.6%) were full-term infants. While the rate of hyperglycemia was 6.9% in all of the patients; it was found higher in preterm group (12.7%) than that of full-term group (4.95 %), (p<0.05). Weight gain was noticed in 10 preterm (10/23) and one fullterm infants (1/19) due to excess parenteral fluid administration during transport of neonates. Respiratory distress syndrome (44.2%), asphyxia-acidosis (36.5%), infection (32.7%), and use of total parenteral nutrition (23.1%) or medications (9.6%) were the main underlying causes of the hyperglycemia in preterm group. In full-term group, asphyxia-acidosis (58.3%), infection (26.7%), exchange transfusion (25%), and peritoneal dialysis (10%) were the main causes of hyperglycemia in term group. Insulin treatment was needed in 9 (17.3%) preterm and 4 (6.7%) full-term patients. Of the study patients, 14 (26.9%) preterm and 20 (33.3%) full-term infants died from hyperglycemia/underlying diseases.

Conclusions: In addition to excess parenteral fluid administration and hypothermia during the transportation of neonates, stressful conditions like respiratory distress syndrome, asphyxia-acidosis, and infection are main underlying causes for neonatal hyperglycemia

Keywords: Low birth weight, hyperglycemia, insulin, newborn, preterm infant, outcome

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Copyright © 2010 The Author(s). This is an open access article distributed under the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited.

How to cite

1.
Aydın M, Zenciroğlu A, Aycan Z, Çetinkaya S, Okumuş N, Hakan N, et al. NEONATAL HYPERGLYCEMIA: EVALUATION OF THE DEMOGRAPHYCAL AND CLINICAL CHARACTERISTICS OF OUR PATIENTS. Turk J Pediatr Dis [Internet]. 2010 Jun. 1 [cited 2025 Jul. 8];4(3):158-64. Available from: https://turkjpediatrdis.org/article/view/110