Öz

Objective: Iron containing drugs are one of the most commonly prescribed drugs in our country and accidental or

suicidal poisoning continues to be an important pediatric emergency. Our aim was to evaluate the clinical, laboratory,

radiologic findings, and treatment approaches of children hospitalized with acute iron poisoning.

Material and Methods: The clinical, laboratory, and radiologic findings of and treatment approaches for 17 patients

aged 14 months-15 years hospitalized with acute iron poisoning were reviewed.

Results: The mean age was 37±35.2 months. Iron poisoning was accidental in 16 patients. The mean duration

between drug intake and hospital admission was 177±149 minutes. The mean ingested amount of iron was 35.4±19

mg/kg. The mean blood iron level was 232±136 mcg/dl. There was no significant relationship between the reported

dose of ingested iron and the blood iron level (p>0.05). There was no significant relationship between blood iron level

and ingestion time (p>0.05). Laboratory results revealed metabolic acidosis in 3 patients, respiratory acidosis in one

patient, leucocytosis in one patient, and prolonged activated partial thromboplastin time in one patient. The patients’

findings were not consistent with blood iron levels. Whole bowel irrigation and IV deferoxamine were used in 3 patients.

There was no death. The mean hospitalization duration was 2.8±1.1 days.

Conclusion: Accidental iron poisoning continues to be an important pediatric emergency. There are no correlations

between blood iron levels and the amount of ingested iron or the ingestion time. There was also no correlation between

the blood iron levels and the clinical, laboratory and radiographic findings in our study.

Anahtar Kelimeler: Iron, Fe+2, Fe+3

Referanslar

  1. 1. Jayashree M, Singhi S. Changing trends and predictors of outcome
  2. in patients with acute poisoning admitted to the intensive care. J
  3. Trop Pediatr 2011;57:340-6.
  4. 2. Smolinske SC, Kaufman MM. Consumer perception of household
  5. hazardous materials. Clin Toxicol 2007;45:522-5.
  6. 3. Chang TP, Rangan C. Iron poisoning: A literature-based review of
  7. epidemiology, diagnosis, and management. Pediatr Emerg Care
  8. 2011;27:978-85.
  9. 4. Baranwal AK, Singhi SC. Acute iron poisoning: Management
  10. guidelines. Indian Pediatr. 2003;40:534-40.
  11. 5. Madiwale T, Liebelt E. Iron: Not a benign therapeutic drug. Curr
  12. Opin Pediatr 2006;18:174-9.
  13. 6. Skoczynska A, Kwiecinska D, Kielbinski M, Lukaszewski M. Acute
  14. iron poisoning in adult female. Hum Exp Toxicol 2007;26:663-6.
  15. 7. Porter JB. Concepts and goals in the management of transfusional
  16. iron overload. Am J Hematol 2007;82:1136-9.
  17. 8. Sipahi T, Karakurt C, Bakirtas A, Tavil B. Acute iron ingestion. Indian
  18. J Pediatr 2002;69:947-9.
  19. 9. Phillips S, Gomez H, Brent J. Pediatric gastrointestinal
  20. decontamination in acute toxin ingestion. J Clin Pharmacol
  21. 1993;33:497-507.
  22. 10. Carlsson M, Cortes D, Jepsen S, Kanstrup T. Severe iron
  23. intoxication treated with exchange transfusion. Arch Dis Child
  24. 2008;93:321-2.
  25. 11. Sankar J, Shukla A, Khurana R, Dubey N. Near fatal iron intoxication
  26. managed conservatively. BMJ Case Rep 2013; doi:10.1136/bcr-
  27. 2012-007670.
  28. 12. Gumber MR, Kute VB, Shah PR, Vanikar AV, Patel HV, Balwani
  29. MR, et al. Successful treatment of severe iron intoxication with
  30. gastrointestinal decontamination, deferoxamine, and hemodialysis.
  31. Renal failure 2013;35:729-31.

Nasıl atıf yapılır

1.
Şenel S. Acute Iron Poisoning in Children: An Ongoing Important Pediatric Emergency. Turk J Pediatr Dis [Internet]. 2018 Dec. 30 [cited 2025 May 24];12(4):247-50. Available from: https://turkjpediatrdis.org/article/view/490