Öz

Streptococcus pneumoniae çocukluk çağındaki menenjit, bakteriyemi, pnömoni ve otitlerin en önemli nedenidir. Pnömokokkal enfeksiyonların tanısı halen problemdir. Binax NOW, idrarda S. pneumoniae C- polisakkarit antijenini tarayan hızlı bir immunkromotografik testtir (İKT).Biz çalışmamızda, çocuklardaki pnömokok enfeksiyonlarının tanısında İKT in kullanılabilirliğini araştırdık. Çalışmamıza 50 sağlıklı çocuk (kontrol grubu) ile sepsis, pnömoni, otit ve menenjit tanılı 50 çocuk (hasta grubu) alındı. Tüm olgulardan idrar örnekleri ve nasofaringeal kültürler elde edildi. Ayrıca hasta grubunda uygun olan olgulardan kan, transtrekeal aspirat, idrar ve BOS (beyin omurilik sıvısı) örnekleri alındı.Kontrol grubunda 7 olguda ve hasta grubunda da 10 olguda üriner antijen pozitifliği bulduk. Nazofarinkslerinde S. pneumoniae taşıyan 3 çocuktan (1 kontrol grubunda, 2 hasta grubunda) hepsinde IKT pozitifti. Biz 1 kan kültüründe, 2 BOS kültüründe olmak üzere 3 olguda pnömokok saptadık. Hepsinde İKT pozitifti. Antimikrobial tedavinin, aşılamanın ve akut faz reaktan düzeylerinin üriner antijen tarama testi üzerine etkisi yoktu.Biz, çocuklardaki pnömokoksik enfeksiyonların tanısında yüksek taşıyıcılık oranlarının yanlış pozitifliğe yol açması nedeniyle bu testin kullanılabilir olmadığı sonucuna vardık. Bu test, sadece diğer geleneksel mikrobiyolojik yöntemlerle birlikte destekleyici yöntem olarak denenebilir.

Anahtar Kelimeler: Streptokokus pnömonia, üriner antijen, çocuk

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Telif hakkı ve lisans

Nasıl atıf yapılır

1.
Önder A, Vardar F, Çiftdoğan DY, Bayram N. Çocuklarda Pnömokok Enfeksiyonlarında Üriner Antijen Taraması. Turk J Pediatr Dis [Internet]. 2012 Aug. 1 [cited 2025 May 25];6(2):69-75. Available from: https://turkjpediatrdis.org/article/view/176