Abstract

Objective: Various methods have been investigated to prevent postoperative peritoneal adhesions. It is thought that hypertonic solutions could be used to prevent peritoneal adhesions with waterisation. The aim of this study was to investigate the role of 50% dekstrose solution in the formation of PPA.

Material and Methods: Rats were divided into 3 groups, each consisting of twelve rats. Groups were classified as; 50% dekstrose, sham and control group. The rats were sacrified on the 14th day and relaparotomies were performed. The results were evaluated macroscopically and microscopically according to predetermined classifications.


Results: When the groups treated with 50% dekstrose were compared with the control groups according to the previously described macroscopic (Nair) and microscopic (Zuhlke) classifications, there was no significant difference in PPA formation both microscopically and macroscopically.


Conclusion: In the experimentally created adhesion model, the effect of 50% dekstrose on preventing PPA formation could not be proved.

Keywords: Postoperative peritoneal adhesions (PPA), 50% dekstrose, adhesion in rats

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How to cite

1.
Demirtaş G, Bostancı SA, Güney D, Hücümenoğlu S, Tiryaki T. The Role of 50% Dekstrose For Preventing Postoperative Peritoneal Adhesions in Adhesive Intestinal Obstruction in Rats. Turk J Pediatr Dis [Internet]. 2022 May 30 [cited 2025 May 25];16(3):220-4. Available from: https://turkjpediatrdis.org/article/view/888