Abstract
Objective: We investigated the frequency of Helicobacter Pylori (HP) infection in children with Henoch-Schönlein purpura (HSP).
Material and Methods: The study involved 61 patients with HSP and 62 healthy controls of similar age between July 2009 and December 2011. HP IgG and IgA levels were evaluated by the ELISA method in all patients and controls.
Results: The HP IgG and IgA seropositivity rates were 55.7% and 60.6% in HSP patients (mean age 8.53±3.8 years, F/M: 32/29) and HP IgG seropositivity was 61.3% in normal controls (mean 9.1±3.3 years, F/M: 30/32). There was no statistical difference between the two groups. The HP IgG seropositivity rate was 64.5% in patients with abdominal pain and 60% in those with epigastric pain. There was no signifi cant relationship between HP seropositivity and the degree of abdominal complaints.
Conclusion: HP seropositivity was found in up to 60% percent of healthy control subjects, indicating that HP infection begins in early childhood. It is an important public health problem as it can cause many other disorders in addition to its effects on the gastrointestinal system. The HP seropositivity rate was high in HSP patients but not different from healthy controls
Keywords: Antibodies, Child, Helicobacter pylori, Henoch-Schoenlein purpura
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