Abstract
Celiac disease is extremely common. The classical presentation tends to occur in younger children, while atypical presentations occur at an older age. Knowledge about the varied clinical manifestations together with CD screening and diagnosis lead to appropriate early diagnosis and intervention in affected children. Although serologic testing has become more reliable, there still remain significant problems with testing, particularly in children under 2 years old. Genes encoding HLA DQ2 or DQ8 are found in the vast majority of those with CD, and negative test results can be useful in ruling out the disorder. All patients should undergo a duodenal biopsy while on a gluten-containing diet in order to diagnose CD before a gluten-free diet (GFD) is recommended. A GFD should be offered to all children diagnosed with CD even when perceived as asymptomatic
Keywords: Child, Celiac disease
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