Abstract
Aim: The aim of this study is to evaluate the clinical and demographic characteristics of patients with antibody defi ciency in our allergy clinic. Material-
Method: The medical records of 4600 patients attended to our allergy outpatient clinic between September 2007 and August 2010 were reviewed for accompanying primary antibody defi ciencies.
Results: Ninety-seven (2.1%) of the patients had primary antibody defi ciency. Of these 97 patients, 74 (76.3%) were male (age range: 13-204 months), 21.6 % had parental consanguinity and 4.1% had a family history of immune-defi ciency.The diagnosis of patients were as follows: 62 (63.9%) transient hypogamaglobulinemia, 21 (21.6%) IgA defi ciency, 6 (6.2%) IgG subclass defi ciency, and 8 (8.2%) IgM defi ciency. Their diagnosis in allergy clinic were; 63 asthma, 18 wheezy infant, 6 urticaria, 4 allergic rhinitis, 4 atopic dermatitis, and 2 food allergy.
Conclusion: Primary antibody defi ciencies can be seen together with allergic diseases. During evaluation of allergic patients, primary immune defi ciencies should also be considered
Keywords: Allergic disease, asthma, children, immun-defi ciency, IgA defi ciency
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