Abstract

The most common symptoms of COVID-19 infection are fever and cough; but may cause respiratory, enteric, hepatic, nephrotic, neurological, and skin involvement. Onychomadesis is the proximal separation of the nail plate from the nail matrix due to a temporary cessation of nail growth. Numerous studies about cutaneous manifestations of COVID-19 were reported; however findings of nails were limited. This paper reported a case of onychomadesis which appeared on the nails after a severe COVID-19 infection (MIS-C).

Keywords: Child, COVID-19, Onychomadesis

References

  1. Jayarangaiah A, Kariyanna PT, Chen X, Jayarangaiah A, Kumar A. COVID-19-Associated Coagulopathy: An Exacerbated Immunothrombosis Response. Clin Appl Thromb Hemost Jan-Dec 2020;26:1076029620943293.
  2. Loomba RS, Villarreal EG, Flores S. COVID-19 and Hyperinflammatory Syndrome in Children: Kawasaki Disease with Macrophage Activation Syndrome in Disguise?. Cureus 2020;12:e9515.
  3. Zhang Q, Bastard P, Liu Z, Le Pen J, Velez MM, Chen J, et al. Inborn errors of type I IFN immunity in patients with life-threatening COVID-19. Science 2020;370:eabd4570.
  4. Hardin J, Haber RM. Onychomadesis: Literature Review. Br J Dermatol 2015;172:592-6.
  5. Scarfi F, Arunachalam M, Galeone M, Difonzo EM. An uncommon onychomadesis in adults. Int J Dermatol 2014;53:1392-4. 5.
  6. Chiu HH, Lan CCE, Wu CS, Kuo KC, Chen GS, Wei KC. Onychomadesis Following Hand-Foot and Mouth Disease. Cutis 2016;97:E20-1.
  7. Damevska K, Gocev G, Pollozahani N, Nikolovska S, Neloska N. Onychomadesis Following Cutaneous Vasculitis. Acta Dermatovenerol Croat 2017;25:77-9.
  8. Becker RC. Covıd-19 associated vasculitis and vasculopathy. J Thromb Thrombolysis 2020;50:499-511.
  9. Li D, Wu Y, Xing X, Huang J, Mao A, Liu T, et al. Onychomadesis and potential association with HFMD outbreak in a kindergarten in Hubei province, China, 2017. BMC Infect Dis 2019;19:995.
  10. Senturk N, Ozdemir H. Onychomadesis following COVID-19 infection: Is there a relationship?. Dermatol Ther 2020;e14309.
  11. Alobaida S, Lam JM. Beau lines associated with COVID-19. CMAJ 2020;192:E1040.
  12. Jimenez-Cauhe J, Ortega-Quijano D, Prieto-Barrios M, Moreno-Arrones OM, Fernandez-Nieto D. Reply to “COVID-19 can present with a rash and be mistaken for Dengue”: Petechial rash in a patient with COVID-19 infection. J Am Acad Dermatol 2020 2020;83:e141-e142.

Copyright and license

How to cite

1.
Metbulut AP, Metin A, Alim Aydın S, Gülhan B, Özkaya Parlakay A. A Child with Severe COVID-19 Complicated with Onychomadesis. Turk J Pediatr Dis [Internet]. 2022 May 30 [cited 2025 May 24];16(3):242-5. Available from: https://turkjpediatrdis.org/article/view/892