References
- Toksöz A, Teber S. Efficacy and safety of levetiracetam treatment in childhood epilepsy. Turk J Pediatr Dis. 2025;19:312-6. https://doi.org/10.12956/TJPD.2025.1221
- Martins JMB, Vieira PLF, Gosch Berton G, et al. Levetiracetam versus carbamazepine monotherapy in the management of pediatric focal epilepsy: a systematic review and meta-analysis of randomized controlled trials. Eur J Pediatr. 2024;183:4623-33. https://doi.org/10.1007/s00431-024-05768-0
- Yıldırım M, Bektaş Ö, Göktaş ÖA, Yüksel MF, Şahin S, Teber ST. Levetiracetam monotherapy in children with epilepsy: Experience from a tertiary pediatric neurology center. Epilepsy Behav. 2021;116:107745. https://doi.org/10.1016/j.yebeh.2020.107745
- Scheffer IE, Berkovic S, Capovilla G, et al. ILAE classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology. Epilepsia. 2017;58:512-21. https://doi.org/10.1111/epi.13709
- Liu Y, Wang Y, Li X, Wu X. Efficacy and safety of levetiracetam vs. oxcarbazepine in the treatment of children with epilepsy: A systematic review and meta-analysis. Front Pediatr. 2024;12:1336744. https://doi.org/10.3389/fped.2024.1336744
- Hadzagic Catibusic F, Uzicanin S, Vukas Salihbegovic E, Huseinbegovic Z. Efficacy and safety of levetiracetam for childhood epilepsies. Med Arch. 2024;78:122-6. https://doi.org/10.5455/medarh.2024.78.122-126
- Ganjikunta RK, Udaragudi RD, Chalivendra P, Kaveti UR, Mallaram GK. From seizures to behavioral symptoms: A case series of psychiatric adverse effects of levetiracetam in epilepsy patients. Cureus. 2025;17:e96957. https://doi.org/10.7759/cureus.96957
- Halma E, de Louw AJA, Klinkenberg S, Aldenkamp AP, IJff DM, Majoie M. Behavioral side-effects of levetiracetam in children with epilepsy: a systematic review. Seizure. 2014;23:685-91. https://doi.org/10.1016/j.seizure.2014.06.004
- Nickels KC, Zaccariello MJ, Hamiwka LD, Wirrell EC. Cognitive and neurodevelopmental comorbidities in pediatric epilepsy. Nat Rev Neurol. 2016;12:465-76. https://doi.org/10.1038/nrneurol.2016.98
- Verrotti A, D’Adamo E, Parisi P, Chiarelli F, Curatolo P. Levetiracetam in childhood epilepsy. Paediatr Drugs. 2010;12:177-86. https://doi.org/10.2165/11316250-000000000-00000
- Biset G, Abebaw N, Gebeyehu NA, et al. Prevalence, incidence, and trends of epilepsy among children and adolescents in Africa: A systematic review and meta-analysis. BMC Public Health. 2024;24:771. https://doi.org/10.1186/s12889-024-18236-z
- Bankole NDA, Dada TE, Mchome B, et al. Epilepsy care and outcome in low- and middle-income countries: A scoping review. J Neurosci Rural Pract. 2024;15:8-15. https://doi.org/10.25259/JNRP_527_2023
- Sokhi DS, Samia P. Epilepsy prevalence studies and the lingering treatment gap in Africa. Lancet Glob Health. 2024;12:e1221-2. https://doi.org/10.1016/S2214-109X(24)00272-9
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Copyright © 2026 The Author(s). This is an open access article distributed under the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited.
How to cite
1.
Iddir S, Brahim L, Benlahreche Z batoul. Comment on “Levetiracetam in childhood epilepsy: Expanding the evidence base”. Turk J Pediatr Dis. 2026;20(5):391-393. https://doi.org/10.12956/TJPD.2026.1354
